Ilaprazole Sodium for Injection has equivalent efficacy to traditional PPIs, yet features a lower dosage requirement, does not occupy intravenous access, and has fewer drug-drug interactions, which greatly enhances the convenience of clinical medication.
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Privacy As a domestic innovative drug in China that has broken the monopoly in the field of imported PPIs, Ilaprazole Sodium for Injection is an important clinical medication in the digestive system field, providing a highly effective and convenient option of intravenous acid-suppressive treatment for the clinical diagnosis and treatment of diseases associated with upper gastrointestinal bleeding.
1、Peptic ulcer bleeding.
2、Prevention of stress ulcer bleeding in critically ill patients.
Peptic ulcer bleeding: For intravenous infusion, the initial dose is 20mg, followed by 10 mg once daily for 3 consecutive days. After the course of treatment, oral therapy may be initiated as appropriate.
Prevention of stress ulcer bleeding in critically ill patients: For intravenous infusion, the initial dose is 20mg, followed by 10mg once daily. The initiation and discontinuation of administration shall be determined based on the clinician's judgment on whether the patient is in a critical condition and at risk of stress ulcer bleeding. No clinical trial data is available for administration lasting more than 14 days.
For high-risk patients with spurting bleeding, oozing bleeding, exposed blood vessels and other conditions, endoscopic hemostasis shall be performed first.
This product is for intravenous infusion only: Dissolve 10mg of this product completely in 100ml of 0.9% Sodium Chloride Injection, and administer via intravenous infusion using an infusion set with a filtration device over 30 minutes. For an initial dose of 20mg, dissolve the product in 200ml of 0.9% Sodium Chloride Injection. The prepared solution must be used up within 3 hours.
This product can only be dissolved in 0.9% Sodium Chloride Injection for intravenous use. The prepared solution shall not be mixed with other drugs nor administered through the same infusion device.
Contraindicated in patients with hypersensitivity to ilaprazole and other benzimidazole compounds.
Contraindicated in patients with hypersensitivity to any other ingredients of this product.
Common: Elevated alanine aminotransferase, elevated aspartate aminotransferase.
Uncommon: Elevated serum alkaline phosphatase, elevated γ-glutamyl transferase, elevated serum bilirubin.
Common: Fever.
Uncommon: Hypocalcemia, hypernatremia.
Uncommon: Hiccups, constipation, abdominal distension.
Common: Decreased white blood cell count.
Uncommon: Elevated serum lactate dehydrogenase, elevated serum creatinine, elevated serum urea, decreased platelet count, increased total bile acid.
No clinical trial data on the use of this product in pregnant and lactating women is available to date, and its use is not recommended for this population. If a lactating woman must receive treatment with this product, breastfeeding should be discontinued.
No clinical trial data in pediatric patients is available to date.
Ilaprazole Sodium for Injection was administered to 151 geriatric patients aged 60 years and above in two clinical trials, and no significant differences in its safety and efficacy were observed between this population and the general population.
For more detailed drug information, please consult the official package leaflet.
If any issues arise, please contact us immediately.
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